Our research projects Filtre Biologie cellulaire Ciblage thérapeutique Développement Différenciation cellulaire Epigénétique Cellules souches Génétique Génomique et régulation du génome Hématologie Immunité adaptative Immunité innée Immunothérapie Métabolisme Microbiote Reproduction et périnatalité Signalisation cellulaire Vieillissement Cancer COVID-19 Diabète et autres maladies métaboliques Infections bactériennes Infections parasitaires Infections virales Maladies auto-immunes Maladies inflammatoires chroniques Maladies rares SIDA/VIH Maladies de la reproduction et de la grossesse Choose Disease/Research area Immunologie Cancer Métabolisme et endocrinologie Microbiologie Plasticité cellulaire et reproduction Plateformes technologiques Choose Scientific axis Key words Filtrer Role of transcription factor Foxo1 in T-cell functions and immunosenescence Bruno LUCAS Immunology Project 1 - Mechanisms of phagocytosis in normal conditions Florence NIEDERGANG Microbiology Immunology Project 2 - Antigen capture, release and presentation by dendritic cells Fatah OUAAZ Immunology Microbiology Project 3 - Perturbations of the phagocytic and activation functions of macrophages by viral infections (HIV, YFV) Florence NIEDERGANG Suzanne FAURE-DUPUY Microbiology Immunology Project 5 - Role of the interferon B response on microglia activation and neuron/microglia crosstalk Eliette BONNEFOY Microbiology Immunology Genetics of diabetes Our main aim is to identify and study genes involved in juvenile-onset diabetes, ranging from type 1 diabetes (T1D) to… Cécile JULIER Cellular plasticity and reproduction Metabolism and endocrinology Endothelial cell response to infection by Neisseria meningitidis Our team studies the intricate interactions of Neisseria meningitidis (meningococcus) with human peripheral and brain vasculatures, two interactions at the… Sandrine BOURDOULOUS Microbiology Key adaptation mechanisms of N. meningitidis to its human host We have demonstrated that the capacity of N. meningitidis to bind to peripheral and brain endothelial cells relies on the… Philippe MORAND Microbiology Inhibition of the tyrosine kinase receptor ErbB2/HER2: from bacterial meningitis to human cancers Among the ErbB family of tyrosine kinase receptors, ErbB2/HER2 displays unique properties. This orphan receptor exists in a ligand-independent, activated… Camille FAURE Cancer IL-7 in mucosal immunity Anne COUEDEL-COURTEILLE Magali RANCEZ Immunology Microbiology O-GlcNAcylation, cell signaling and physiopathological regulations Tarik ISSAD Metabolism and endocrinology Cellular plasticity and reproduction Control of the intestinal barrier function by the local action of insulin Sandra GUILMEAU Metabolism and endocrinology Cellular plasticity and reproduction 2 3 4 5 6 7 8 9 10