15 microscopes
5 networks
261 articles of which 80 with signature
260 trainings/year
3 Masters and 2 National trainings
Team members
Scientific Board
Equipments
- 1 Imaging Flow Cytometer
- 2 Super-Resolution microscopes
- 2 Multi-photon microscopes
- 4 Confocal microscopes
- 5 Wide-field microscopes
- 2 Macroscopes
- 1 Vibratome
- 1 3D Printer
- Pump
Services
- Tissue clearing
- Super-resolution microscopy SMLM : STORM, PALM, sptPALM, 3DSTORM
- Super-resolution microscopy STED : STED-FLIM, 3D-STED, ExSTED
- Expansion microscopy ExM : ProExM, TREx6, ExPath, ExSTED
- Sectioning of thick tissues ( ~ 400µm) frais, fixed
- Intra-vital imaging
- Biosafety Level 2 BSL-2 (tissue of human origin)
- Biosafety Level 3 BSL-3 (host-pathogen interaction, bacteria, parasites, viruses)
- Images processing (Segmentation, Deep learning, Histo-cytometry, Tracking)
- Cochin Image Database
Applications
- Cellular and molecular imaging
- Super-résolution : STORM PALM STED STED-FLIM ExM
- FRET FRET-FLIM FLIM Phasor
- FRAP
- Cell migration
- Biosensors: Ca2+, pH, NaDH, Red/Ox, membrane tension
- Tissue imaging
- mouse models, fish, ovo, spheroid
- Cell migration
- Perfusion medium, anesthesia system, Intra-vital Imaging
- SHG and THG contrast (collagen I and III, bone, fibrogenesis, sarcomeres)