15 microscopes

5 networks

250 articles of which 75 with signature

260 trainings/year

3 Masters and 2 National trainings

Equipments

  • 1 Imaging Flow Cytometer
  • 2 Super-Resolution microscopes
  • 2 Multi-photon microscopes
  • 4 Confocal microscopes
  • 5 Wide-field microscopes
  • 2 Macroscopes
  • 1 Vibratome
  • 1 3D Printer
  • Pump

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DIVE
prestation coupe

Services

  • Tissue clearing
  • Super-resolution microscopy SMLM : STORM, PALM, sptPALM, 3DSTORM
  • Super-resolution microscopy STED : STED-FLIM, 3D-STED, ExSTED
  • Expansion microscopy ExM : ProExM, TREx6, ExPath, ExSTED
  • Sectioning of thick tissues ( ~ 400µm) frais, fixed
  • Intra-vital imaging
  • Biosafety Level 2 BSL-2 (tissue of human origin)
  • Biosafety Level 3 BSL-3 (host-pathogen interaction, bacteria, parasites, viruses)
  • Images processing (Segmentation, Deep learning, Histo-cytometry, Tracking)
  • Cochin Image Database

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Applications

  • Cellular and molecular imaging
    • Super-résolution : STORM PALM STED STED-FLIM ExM
    • FRET FRET-FLIM FLIM Phasor
    • FRAP
    • Cell migration
    • Biosensors: Ca2+, pH, NaDH, Red/Ox, membrane tension
  • Tissue imaging
    • mouse models, fish, ovo, spheroid
    • Cell migration
    • Perfusion medium, anesthesia system, Intra-vital Imaging
    • SHG and THG contrast (collagen I and III, bone, fibrogenesis, sarcomeres)

Networks

Contact

Pierre Bourdoncle

22 rue Méchain
75014 Paris

Contact by email

Location

Roussy building

Localisation

Localisation

Alumni