Florence Niedergang, director
Florence Niedergang is an internationally recognized expert in the field of phagocytosis. She heads the "Biology of Phagocytes, Infection and Immunity" team.
Florence Niedergang studied biochemistry and immunology at ENS Cachan and Paris Diderot University. She obtained her PhD in 1997 for studies on the activation of T lymphocytes at Institut Pasteur. With the financial support of the ARC and EMBO foundations, she is doing a post-doctorate at the University of Lausanne (Switzerland) where she is studying the role of dendritic cells and macrophages in the absorption and survival of bacteria in the intestine. In 2001, she was recruited as a CNRS research fellow at Institut Curie to dissect the molecular mechanisms of phagocytosis in macrophages. In 2005, she joined Institut Cochin as group leader, funded by emergence programs from the CNRS (ATIP) and the City of Paris. His team is interested in the mechanisms of clearance and activation of phagocytic cells, both under normal and pathological conditions such as viral infections.
Florence Niedergang is the author of 67 publications, 6 book chapters and 3 patents. She is a member of the scientific council of the Institute of Biological Sciences of the CNRS (INSB), co-coordinator of the Paris Center Node of the national infrastructure France BioImaging, co-director of the GDR AQV ('Quantitative Approaches to Life'), co -director of Microb'UP, "Institut Hors Murs Microbiologie", Université Paris Cité and president of the French Society of Cellular Biology (SBCF).
In 2017, she was elected director of the "Infection, Immunity and Inflammation" department. In 2022, she was appointed director of Institut Cochin.
Sophie Vaulont, deputy director
Sophie Vaulont is research director at Inserm, author of major advances in the regulation of iron homeostasis. She is deputy scientific director of Institut Cochin.
Sophie Vaulont studied biochemistry, molecular biology and physiology at Pierre and Marie Curie University. She obtained her PhD in 1987 in the laboratory of Prof. Axel Kahn at Institut Cochin and was recruited as a research fellow at Inserm in 1988. In 1994, she joined the laboratory of Prof. Martin Evans (Wellcome CRC, UK) for a sabbatical year to improve his knowledge of mouse genetic engineering. For two consecutive terms, 2010-2013 & 2014-2018, she led, with Benoit Viollet, a team at Institut Cochin, studying the molecular mechanisms allowing the control of energy metabolism and iron homeostasis. The team identified the roles of the iron-regulating hormone hepcidin, as well as that of AMPK, the AMP-activated protein kinase, a sensor of energy status in various pathophysiological conditions and were able to assess the usefulness and efficacy of these molecules in theranostics.
Winner of several prizes, Sophie Vaulont was elected a member of the International Society of BioIron in 2005, from which she received the 2005 Marcel Simon Prize for the discovery of hepcidin. She is the author of more than 135 articles, 2 patents and several book chapters, editorials and review articles. She was appointed member of the Specialized Scientific Committee (CSS) 3 Inserm from 2016 to 2021.
From 2012 to 2017, Sophie Vaulont was director of the Endocrinology, Metabolism and Diabetes (EMD) department at Institut Cochin. In 2017, she became deputy director of the institute, first alongside Pierre Olivier Couraud, and since January 2022, the new director, Florence Niedergang.
Yannick Allanore, deputy director
Yannick Allanore is professor of rheumatology at Université Paris Cité and director of the academic musculoskeletal department of Paris Center hospitals.
Yannick Allanore obtained his PhD in 2004 in the biochemistry department of Cochin Hospital, on the role of oxidative stress in systemic sclerosis (SSc), a rare autoimmune disease. He joined Necker Hospital as a post-doctoral fellow in 2005 where he developed several projects on immunogenetics in SSc. In 2010, he joined Institut Cochin as part of an ATIP-AVENIR program. Since 2018, he leads a team working on the pathogenesis of fibro-inflammatory diseases and studies biomarkers and drug candidates of these diseases, using a platform of related and complementary animal models. In 2022, he was appointed deputy director of Institut Cochin.
Prof. Allanore is a member of several professional associations and groups, including the French Society of Rheumatology and the American College of Rheumatology. He is the former elected President (2013-2019) of the European Scleroderma Testing and Research Group (EUSTAR). He is a member of the steering committee of the World Scleroderma FOUNDATION. He has published over 450 articles and edited several books.
Noémie Marrant, general secretary
Noémie Marrant has dual expertise in human resources and administration management. She has built her career within hospital structures and in the academic research world.
Noémie Marrant holds a master's degree in economic and social administration, "human resources" option, and a DESS in "executives for social sector organizations" from the University of Paris-Panthéon-Sorbonne. After beginning her career in 2006 at Bicêtre Hospital, where she was assistant to the HRD and then pole administrative manager, she discovered the world of research by joining the ANRS in 2009. Subsequently, she served as head of human resources for medical staff at the Maison Blanche hospital (GHU Paris psychiatry and neurosciences) before becoming General Secretary of Institut Cochin.