Vascular Control of Organ Growth and Regeneration

Karina Yaniv (Weizmann Institute of Science, Israel)

18 December 2024

Seminar

Pratical info

12:00 - 13:00

Conference room Rosalind Franklin

research professional

Reduced mobility access

Prof. Yaniv is the Head of the Aharon Katzir-Katchalsky Center (Weizmann Institute of Science). Her lab seeks to elucidate the cellular and molecular mechanisms governing the formation of blood and lymphatic vessels during embryonic development, organogenesis and regeneration. During her postdoctoral studies Dr. Yaniv identified and characterized the well-established lymphatic system of the zebrafish (Nat. Med., 2006), and has since continued studying the cellular origins and molecular mechanisms controlling the formation of lymphatic vessels, at her own lab. Taking advantage of the ability of zebrafish to efficiently regenerate most of their organs, the Yaniv lab investigates the involvement of lymphatic vessels in the processes of tissue inflammation, fibrosis, repair and regeneration.

Among her academic and professional awards and honors are the Levinson Prize in Biology (2017), the Wendy Chaite Leadership Award by the Lymphatic Education and Research Network (2016), ERC-StG (2013), ERC-CoG (2018), the Israel Cancer Research Foundation Career Development Award (2012), the Werner-Risau-Prize for outstanding research in vascular biology (2007), an EMBO postdoctoral fellowship (2005-2007), a Susan G. Komen Young Investigator Scholarship from the Lymphatic Research Foundation (2006), and a Golda Meir Foundation prize for excellence (2003), EVBO Lecture Award (2024) and the most recent one ERC-SyG (2024).

Karina Yaniv is invited by Diana Passaro.

List of publications

Endolysosomal dysfunction in radial glia progenitor cells leads to defective cerebral angiogenesis and compromised blood-brain barrier integrity Nature Communications 2024 Bassi I., Grunspan M., Hen G., Ravichandran K. A., Moshe N., Gutierrez-Miranda L., Safriel S. R., Kostina D., Shen A., Ruiz de Almodovar C. & Yaniv K.
A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA) BioRxiv 2024 Bassi I., Jabali A., Farag N., Egozi S., Moshe N., Leichner G. S., Geva P., Levin L., Barzilai A., Avivi C., Long J., Otterstrom J. J., Paran Y., Barr H., Yaniv K. & Greenberger S.
Generation of specialized blood vessels via lymphatic transdifferentiation Nature 2022 Das R. N., Tevet Y., Safriel S., Han Y., Moshe N., Lambiase G., Bassi I., Nicenboim J., Brückner M., Hirsch D., Eilam-Altstadter R., Herzog W., Avraham R., Poss K. D. & Yaniv K.
How many fish make a mouse? Nature Cardiovascular Research 2022 Tzahor E. & Yaniv K.
Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions JCI Insight 2021 Templehof H., Moshe N., Avraham-Davidi I. & Yaniv K.
VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells Cell Reports 2021 Jerafi-Vider A., Bassi I., Moshe N., Tevet Y., Hen G., Splittstoesser D., Shin M., Lawson N. D. & Yaniv K.
Beyond cells: The extracellular circulating 20S proteasomes Biochimica et Biophysica Acta - Molecular Basis of Disease 2021 Dwivedi V., Yaniv K. & Sharon M.
Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging A Cold Spring Harbor Perspectives in Biology Collection 2020 Das R. N. & Yaniv K.
Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis Frontiers in Physiology 2020 Gutierrez-Miranda L. & Yaniv K.
Formation and Growth of Cardiac Lymphatics during Embryonic Development, Heart Regeneration, and Disease A Cold Spring Harbor Perspectives in Biology Collection 2020 Gancz D., Perlmoter G. & Yaniv K.
BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression Life Science Alliance 2020 Cohen B., Tempelhof H., Raz T., Oren R., Nicenboim J., Bochner F., Even R., Jelinski A., Eilam R., Ben-Dor S., Adaddi Y., Golani O., Lazar S., Yaniv K. & Neeman M.

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