3D chromatin remodelling in the germ line

Aurora Herrera Ruiz (Universitat Autonoma de Barcelona)

02 mars 2023

Séminaire

Infos pratiques

12h00 - 13h00
Salle Rosalind Franklin
Professionnel de recherche
Accès mobilité réduite

The group led by Aurora Herrera Ruiz studies structural, functional and evolutionary aspects of genome organization, paying special attention to the germ line given its role in the transmission of genetic information through generations.

Invited by Julie Cocquet.

Selected publications

Álvarez-González L, Arias-Sardá C, Montes-Espuña L, Marín-Gual L, Vara C, Lister NC, Cuartero Y, Garcia F, Deakin J, Renfree MB, Robinson TJ, Martí-Renom MA, Waters PD, Farré M, Ruiz-Herrera A*. Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals. Cell Rep. 2022 DOI: 10.1016/j.celrep.2022.111839

Álvarez-González#, F. Burden#, D. Doddamani#, R. Malinverni, Emma Leach, C. Marín-García, L. Marin-Gual, A. Gubern, C. Vara, A. Paytuví-Gallart, Marcus Buschbeck, P. Ellis*, M. Farré*, A. Ruiz-Herrera*. 3D chromatin remodeling in the germ line modulates genome evolutionary plasticity. Nature Communications, 2022 DOI: 10.1038/s41467-022-30296-6

C. Vara, A. Paytuví-Gallart, Y. Cuartero, L. Álvarez-González, L. Marín-Gual, F. Garcia, B. Florit-Sabater, L. Capilla, R.A. Sanchéz-Guillén, Z. Sarrate, R.A. Cigliano, W. Sanseverino, J.B. Searle, J. Ventura, M. Marti-Renom, F. Le Dily, A. Ruiz-Herrera*. The impact of chromosomal fusions on 3D genome folding and recombination in the germ line. Nature Communications 2021 DOI: 10.1038/s41467-021-23270-1

C. Vara#, A. Paytuví-Gallart#, Y. Cuartero#, F. Le Dily, F. Garcia, J.Salvà-Castro, L.Gómez-H, E. Julià, C. Moutinho, R. Aiese-Cigliano, W. Sanseverino, O. Fornas, A.M. Pendàs, H.Heyn, P. D. Waters, M. A. Marti-Renom*, A. Ruiz-Herrera*. Three-dimensional genomic structure and cohesin occupancy correlates with transcriptional activity during spermatogenesis. Cell Reports, 2019  DOI: 10.1016/j.celrep.2019.06.037